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In enzymology, a polypeptide N-acetylgalactosaminyltransferase () is an enzyme that catalyzes the chemical reaction :UDP-N-acetyl-D-galactosamine + polypeptide UDP + N-acetyl-D-galactosaminyl-polypeptide Thus, the two substrates of this enzyme are UDP-N-acetyl-D-galactosamine and polypeptide, whereas its two products are UDP and N-acetyl-D-galactosaminyl-polypeptide. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. This enzyme participates in o-glycan biosynthesis and glycan structures - biosynthesis 1. It has 2 cofactors: manganese, and calcium. == Nomenclature == The systematic name of this enzyme class is UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase. Other names in common use include: * protein-UDP acetylgalactosaminyltransferase, * UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase, * UDP-N-acetylgalactosamine:kappa-casein polypeptide, * N-acetylgalactosaminyltransferase, * uridine diphosphoacetylgalactosamine-glycoprotein, * acetylgalactosaminyltransferase, * glycoprotein acetylgalactosaminyltransferase, * polypeptide-N-acetylgalactosamine transferase, * UDP-acetylgalactosamine-glycoprotein, * acetylgalactosaminyltransferase, * UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase, * UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, * UDP-N-acetyl-alpha-D-galactosamine:polypeptide, * N-acetylgalactosaminyltransferase, * UDP-N-acetylgalactosamine-glycoprotein, * N-acetylgalactosaminyltransferase, * UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase, * UDP-N-acetylgalactosamine:polypeptide, * N-acetylgalactosaminyltransferase, and * UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Polypeptide N-acetylgalactosaminyltransferase」の詳細全文を読む スポンサード リンク
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